I've been up there by myself before and camped. I met my neighbors camping next to me and gave them my number and location of where I was hunting, so someone would know to send out the posse if I didn't come back at the right time.
4 whrs are ok but you can't ride them everywhere. Most of the side roads are posted closed to offroad vehicles. You can drive almost anywhere there in a regular truck ( I hunted all over that place as a kid with my Dad's friend in his VW beetle)
Of course the farther you go the farther you have to drag a dead deer, but that's most of the fun.
Churly's right, go down to the thick stuff and wait for a shooter.
BTW it's a $25 fine if you shoot a buck that's too small (over 15" spread, four points on one side) but the court costs in Cumberland Co are like $362.00